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Chicago in residence Artist to discuss Holocaust, women in art See Page 3 Volume 13, Issue 23 Lehig hWeek The campus digest for innovation, news and events South Mountaineer Wrestlers win EIWA, M/W hoopsters fall in Patriot See page 4 March 8,2000 Lehigh, St. Luke's identify enzyme as predictor of cancer survival A seven-year study by Lehigh and St. Luke's Hospital has found the enzyme Cathepsin D to be a userful predictor of survival rates among women who have been treated for lymph node-positive breast cancer. The researchers' article, "Analysis of Cathepsin D in Human Breast Cancer: Usefulness of the Processed 3 lkDa Active Form of the Enzyme as a Prognostic Indicator in Node-Negative and Node-Positive Patients,"has been accepted for publication in Breast Cancer Research and Treatment. Since 1992, the researchers have checked 134 St. Luke's Hospital breast cancer patients for Cathepsin D, which breaks down proteins. The function of the enzyme is not clear, but researchers believe it is abnormally secreted in large amounts when a cell becomes cancerous. When a woman develops breast cancer, Cathepsin D breaks down the surrounding tissues and allows the tumor to spread through the lymph nodes or blood. In their study, researchers also examined tissues from 227 patients with benign breast disease and from 28 with normal tissue (derived from breast reductions). Jack Alhadeff, professor of biochemistry, isolated Cathepsin D from the tissue samples, distinguishing an active form from an inactive form. He found high levels of the active form in women whose cancer recurred, and much lower levels in women with benign tumors. "Of the breast cancer patients in the study, 12 of the women have passed away from the disease and all 12 were in the high-risk group based on the level of Cathepsin D in their tissue," says Alhadeff. "We are following those in the high-risk group to check on recurrence." "In the future, determining who does and does not have high levels of Cathepsin D may determine the type of treatment they receive for breast cancer," says Lee Riley, medical director of St. Luke's Cancer Center and director of surgical research for St. Luke's Hospital. "Right now we have no real way of knowing with certainty who will and won't have a recurrence, so we treat the disease aggressively with a combination of surgery, chemotherapy, radiation and drugs like tamoxifen." The study could also help researchers develop a drug to stop the active form of Cathepsin D from enabling the spread of cancer, says Alhadeff. The project was led by Alhadeff, Riley and Marianne Lange, for- Please See ENZYME, Page 2 IPD students invited again to Smithsonian museum For the second year in a row, a team of students in the Integrated Product Development (IPD) program has been invited to exhibit a product it designed and made at the annual conference of the National Collegiate Inventors and Innovators Alliance (NCIIA). The event, dubbed "March Madness for the Mind," will be held March 8-10 at the Smithsonian Institution's National Museum of American History in Washington, D.C. The annual exhibit of student inventions features models of new products designed and made by 13 teams of student inventors representing universities in California, New York, Colorado, Pennsylvania, Massachusetts and Nevada. Seven Lehigh students will exhibit a Karate Scoring Apparatus, a wireless device that transmits radio signals to a computer to determine when contestants in a karate contest score points. The students have designed the product under the guidance of Arkady Voloshin, professor of mechanical engineering and mechanics. Contestants using the apparatus wear a vest containing electronic sensors and gloves associated with a transmitter operating at a selected frequency and pressure sensitive area. When a valid blow is struck, a target area on the vest transmits a signal. The computer receives both a strike and a target signal to indicate a score. Members of the team are Bryan Capobianco, Michael Frey, Piper Hueffed, Karen Mocarski, Laura Scanlan and Brett Snyder, all seniors majoring in mechanical engineering, and David D'Alessandro, an M.B.A. student. Industry adviser for the project is Jack Plesnik, an entrepreneur from Tobyhanna, Pa., who holds a U.S. patent for the device. The project was funded by NCIIA and the Ben Franklin Technology Center, to which the student team will submit a business plan for start-up funding. In IPD classes, students from business, engineering, and arts and sciences form teams to design, make and draw up marketing plans for new products that are are sponsored and funded by industrial companies. So far, students have completed 100 projects, including a mountain bike front suspension that was displayed at last year's. NCIIA conference. The team that designed and built that project has Photo Courtesy IPD Program Pushing his buttons Piper Hueffed and Brett Snyder try out the karate scoring aparatus that they helped make in their IPD class. been invited to an exhibit of student bicycle inventions at the Smithsonian in May. NCIIA, funded by the Lemelson Foundation of Reno, Nevada, gives grants to colleges to set up teams of student inventors. The Smithsonian's Lemelson Center was established in 1995 with a gift from the Lemelson Foundation, a private philanthropic organization founded by Jerome Lemelson (1923-1997), whose 500 patented inventions covered a wide range of technologies, including flexible manufacturing systems and machine-vision systems. The latter gave rise to the invention of the bar-coding systems used to scan store prices. Zoellner gala to feature trumpeter and pianist Virtuoso trumpeter Sergei Nakariakov will perform with the Bamberg Symphony Chamber Orchestra at "Gala- 2000," a black-tie fundraising concert at the Zoellner Arts Center on Sunday, April 9, at 7 p.m. Nakariakov, 22, who has performed in Europe and North America, will play Mozart's Concerto No. 4 for horn and orchestra on the flugelhorn. He will join his sister, pianist Vera Nakariakova, in Shostakovich's Concerto No. 1 for piano and orchestra, which has an elaborate trumpet part. Nakariakov has released seven CDs since signing a recording contract with Teldec Classics International when he was 14. Nakariakova has performed as soloist and chamber musician at festivals in Canada and Japan. The two perform regularly in Europe. Tickets are $100 for prime concert seating, $250 for prime concert seating and the post-concert reception and $400 for the pre-concert cocktails and dinner, beginning at 4:30 p.m. in the Zoellner courtyard, concert and reception. For more information, call Susan Vengrove, director of development for the arts, at x85322 or 800-523-0565. Web site responds to user demand Off-campus viewership has increased dramatically and hundreds of Web pages have been added, since Lehigh's two new home pages made debuted in late December, and tinkering should soon expand the range of the university's search engines. Visits to some sites, especially the admissions pages, have increased by 35 percent over last year. Visitors come from nearly every nation and continent, but are predominantly from North America with concentrations in Pennsylvania, Virginia, California, New York, New Jersey, Florida, Maryland, Massachusets, Connecticut and Washington D.C. Another popular destination is the athletics department home page, which receives more than 16,500 visitors a month. Most visitors enter Lehigh's site through one of two homepages - a start page for external constituents, or an alternate page that highlights relevant news and Web-based services for people on campus. Combined, the two pages are viewed over 400,000 times per month. "We've never had this kind of timely and detailed information available on the site," said Audra Gaugler, university relations editor and content manager for the new Web site. "Over 1,000 new pages have been created and as many as 20 new stories per week are being added." The shift to a more market- driven Web site results from a 1998 study advising that pages be designed to meet the specific information needs of Lehigh's constituents, and that Lehigh join with technology firms to meet that goal. "The single largest complaint with the" previous site was that visitors couldn't find out what was happening at the university," said Steve Oblas, director of design resources for university relations and project director for the Web initiative. Oblas credits the new, easy- to-use content-management system that allows staff writers to publish work instantly to information categories ranging from academics and alumni, to research, news and sports. Most changes to the site were made in response to comments by users. For example, through a partnership with Embark.com, a leading student recruitment Web site, prospective undergraduate and graduate students can now apply online to any program in Lehigh's four colleges. While refinements and new features are continuously being considered, some new initiatives Please See WEB SITE, Page 3 LEHIGH University LehighWecfc Office of Communications/Design 422 Brodhead Avenue Bethlehem, Pa. 18015-3067 MARIE C. INFO RES RM.306 LINCERMAN BOLTZ CLIENT SERVICES NON-PROFIT MAIL U.S. Postage Paid Permit No. 230 Bethlehem, Pa. 18015 LIBRARY NO.030
Object Description
Title | LehighWeek Volume 13, Issue 23 |
Subject | Lehigh University--Periodicals |
Description | Reports on the past week's news, and schedules of upcoming events, at Lehigh University. Thirty issues yearly, published weekly, except for vacations, during the school year, and once or twice a month during the summer. |
Creator | Lehigh University. Dept. of University Relations. |
Publisher | Lehigh University |
Date | 2000-03-08 |
Type | Text |
Format | newsletters |
File Format | image/tiff |
Extent | 4 pages |
Dimensions | 38 cm. x 28 cm. |
Identifier | SC LSer L522 V13 N16 |
Language | Eng |
Rights | http://rightsstatements.org/vocab/InC/1.0/ |
Catalog Record | https://asa.lib.lehigh.edu/Record/304229 |
Description
Title | [Front cover] |
Identifier | SC LSer L522 V13 N16 001 |
Language | Eng |
Rights | http://rightsstatements.org/vocab/InC/1.0/ |
Catalog Record | https://asa.lib.lehigh.edu/Record/304229 |
Full Text | Chicago in residence Artist to discuss Holocaust, women in art See Page 3 Volume 13, Issue 23 Lehig hWeek The campus digest for innovation, news and events South Mountaineer Wrestlers win EIWA, M/W hoopsters fall in Patriot See page 4 March 8,2000 Lehigh, St. Luke's identify enzyme as predictor of cancer survival A seven-year study by Lehigh and St. Luke's Hospital has found the enzyme Cathepsin D to be a userful predictor of survival rates among women who have been treated for lymph node-positive breast cancer. The researchers' article, "Analysis of Cathepsin D in Human Breast Cancer: Usefulness of the Processed 3 lkDa Active Form of the Enzyme as a Prognostic Indicator in Node-Negative and Node-Positive Patients,"has been accepted for publication in Breast Cancer Research and Treatment. Since 1992, the researchers have checked 134 St. Luke's Hospital breast cancer patients for Cathepsin D, which breaks down proteins. The function of the enzyme is not clear, but researchers believe it is abnormally secreted in large amounts when a cell becomes cancerous. When a woman develops breast cancer, Cathepsin D breaks down the surrounding tissues and allows the tumor to spread through the lymph nodes or blood. In their study, researchers also examined tissues from 227 patients with benign breast disease and from 28 with normal tissue (derived from breast reductions). Jack Alhadeff, professor of biochemistry, isolated Cathepsin D from the tissue samples, distinguishing an active form from an inactive form. He found high levels of the active form in women whose cancer recurred, and much lower levels in women with benign tumors. "Of the breast cancer patients in the study, 12 of the women have passed away from the disease and all 12 were in the high-risk group based on the level of Cathepsin D in their tissue," says Alhadeff. "We are following those in the high-risk group to check on recurrence." "In the future, determining who does and does not have high levels of Cathepsin D may determine the type of treatment they receive for breast cancer," says Lee Riley, medical director of St. Luke's Cancer Center and director of surgical research for St. Luke's Hospital. "Right now we have no real way of knowing with certainty who will and won't have a recurrence, so we treat the disease aggressively with a combination of surgery, chemotherapy, radiation and drugs like tamoxifen." The study could also help researchers develop a drug to stop the active form of Cathepsin D from enabling the spread of cancer, says Alhadeff. The project was led by Alhadeff, Riley and Marianne Lange, for- Please See ENZYME, Page 2 IPD students invited again to Smithsonian museum For the second year in a row, a team of students in the Integrated Product Development (IPD) program has been invited to exhibit a product it designed and made at the annual conference of the National Collegiate Inventors and Innovators Alliance (NCIIA). The event, dubbed "March Madness for the Mind," will be held March 8-10 at the Smithsonian Institution's National Museum of American History in Washington, D.C. The annual exhibit of student inventions features models of new products designed and made by 13 teams of student inventors representing universities in California, New York, Colorado, Pennsylvania, Massachusetts and Nevada. Seven Lehigh students will exhibit a Karate Scoring Apparatus, a wireless device that transmits radio signals to a computer to determine when contestants in a karate contest score points. The students have designed the product under the guidance of Arkady Voloshin, professor of mechanical engineering and mechanics. Contestants using the apparatus wear a vest containing electronic sensors and gloves associated with a transmitter operating at a selected frequency and pressure sensitive area. When a valid blow is struck, a target area on the vest transmits a signal. The computer receives both a strike and a target signal to indicate a score. Members of the team are Bryan Capobianco, Michael Frey, Piper Hueffed, Karen Mocarski, Laura Scanlan and Brett Snyder, all seniors majoring in mechanical engineering, and David D'Alessandro, an M.B.A. student. Industry adviser for the project is Jack Plesnik, an entrepreneur from Tobyhanna, Pa., who holds a U.S. patent for the device. The project was funded by NCIIA and the Ben Franklin Technology Center, to which the student team will submit a business plan for start-up funding. In IPD classes, students from business, engineering, and arts and sciences form teams to design, make and draw up marketing plans for new products that are are sponsored and funded by industrial companies. So far, students have completed 100 projects, including a mountain bike front suspension that was displayed at last year's. NCIIA conference. The team that designed and built that project has Photo Courtesy IPD Program Pushing his buttons Piper Hueffed and Brett Snyder try out the karate scoring aparatus that they helped make in their IPD class. been invited to an exhibit of student bicycle inventions at the Smithsonian in May. NCIIA, funded by the Lemelson Foundation of Reno, Nevada, gives grants to colleges to set up teams of student inventors. The Smithsonian's Lemelson Center was established in 1995 with a gift from the Lemelson Foundation, a private philanthropic organization founded by Jerome Lemelson (1923-1997), whose 500 patented inventions covered a wide range of technologies, including flexible manufacturing systems and machine-vision systems. The latter gave rise to the invention of the bar-coding systems used to scan store prices. Zoellner gala to feature trumpeter and pianist Virtuoso trumpeter Sergei Nakariakov will perform with the Bamberg Symphony Chamber Orchestra at "Gala- 2000," a black-tie fundraising concert at the Zoellner Arts Center on Sunday, April 9, at 7 p.m. Nakariakov, 22, who has performed in Europe and North America, will play Mozart's Concerto No. 4 for horn and orchestra on the flugelhorn. He will join his sister, pianist Vera Nakariakova, in Shostakovich's Concerto No. 1 for piano and orchestra, which has an elaborate trumpet part. Nakariakov has released seven CDs since signing a recording contract with Teldec Classics International when he was 14. Nakariakova has performed as soloist and chamber musician at festivals in Canada and Japan. The two perform regularly in Europe. Tickets are $100 for prime concert seating, $250 for prime concert seating and the post-concert reception and $400 for the pre-concert cocktails and dinner, beginning at 4:30 p.m. in the Zoellner courtyard, concert and reception. For more information, call Susan Vengrove, director of development for the arts, at x85322 or 800-523-0565. Web site responds to user demand Off-campus viewership has increased dramatically and hundreds of Web pages have been added, since Lehigh's two new home pages made debuted in late December, and tinkering should soon expand the range of the university's search engines. Visits to some sites, especially the admissions pages, have increased by 35 percent over last year. Visitors come from nearly every nation and continent, but are predominantly from North America with concentrations in Pennsylvania, Virginia, California, New York, New Jersey, Florida, Maryland, Massachusets, Connecticut and Washington D.C. Another popular destination is the athletics department home page, which receives more than 16,500 visitors a month. Most visitors enter Lehigh's site through one of two homepages - a start page for external constituents, or an alternate page that highlights relevant news and Web-based services for people on campus. Combined, the two pages are viewed over 400,000 times per month. "We've never had this kind of timely and detailed information available on the site," said Audra Gaugler, university relations editor and content manager for the new Web site. "Over 1,000 new pages have been created and as many as 20 new stories per week are being added." The shift to a more market- driven Web site results from a 1998 study advising that pages be designed to meet the specific information needs of Lehigh's constituents, and that Lehigh join with technology firms to meet that goal. "The single largest complaint with the" previous site was that visitors couldn't find out what was happening at the university," said Steve Oblas, director of design resources for university relations and project director for the Web initiative. Oblas credits the new, easy- to-use content-management system that allows staff writers to publish work instantly to information categories ranging from academics and alumni, to research, news and sports. Most changes to the site were made in response to comments by users. For example, through a partnership with Embark.com, a leading student recruitment Web site, prospective undergraduate and graduate students can now apply online to any program in Lehigh's four colleges. While refinements and new features are continuously being considered, some new initiatives Please See WEB SITE, Page 3 LEHIGH University LehighWecfc Office of Communications/Design 422 Brodhead Avenue Bethlehem, Pa. 18015-3067 MARIE C. INFO RES RM.306 LINCERMAN BOLTZ CLIENT SERVICES NON-PROFIT MAIL U.S. Postage Paid Permit No. 230 Bethlehem, Pa. 18015 LIBRARY NO.030 |
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